Children’s Hospital of Wisconsin

The Sickle Cell Research Program at Children’s Hospital of Wisconsin Research Institute and the Medical College of Wisconsin is one of 11 sites funded by the National Heart Lung and Blood Institute. Sickle cell research programs are a collaboration of Children’s Research Institute, the Medical College, BloodCenter of Wisconsin’s Blood Research Institute and the MACC Fund.

Our researchers have studied:
-Hemolysis-induced vascular injury in sickle cell disease
-Red blood cell adhesion in sickle cell disease
-The mechanisms by which proinflammatory lipids and high-density lipoproteins function to impair vasodilation in sickle cell disease
-Cysteinyl leukotrienes receptor inhibitors as a target for decreasing sickle cell disease-related morbidity
-Pain outcomes in human sickle cell disease
-Quality of life in children with sickle cell disease