Google
Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Sickle Cell Anemia with Splenic Sequestration
source: Family Practice Notebook
year: 2018
summary/abstract:Sickle Cell Anemia with Splenic Sequestration:
II. Epidemiology
Most common in ages 1 to 4 years old
III. Pathophysiology
A. Splenic infarction typically occurs by Puberty in patients with Hemoglobin SS
B. However, less severe forms of Sickle Cell Disease can occur in adulthood
IV. Precautions
Rapidly progressive course with significant risk of decompensation secondary to acute Anemia
V. Signs
A. Anemia
B. Abdominal Pain
C. Splenomegaly
1. Acute splenic enlargement (especially in under age 5 years, before auto-infarction)
2. Contrast with Sickle Cell Hemolytic Crisis in which the Spleen will be small or non-palpable
+myBinderRelated Content
-
Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with...BACKGROUND: Oxidative stress is thought ...
-
Methacholine challenge test reveals a high prevalence of subclinical severe airway hyper-reactivity in children and ...A total of 67 patients with SCD and 14 u...
-
Differences in Brain Oxygen Supply May Explain Silent Strokes in SCD PatientsBrain oxygen supply is different in diff...
-
The Role of Sleep Impairments on Pain Severity in Adults With Sickle Cell DiseaseSleep is a complex process and impairmen...
-
Sickle Cell and Young Stroke SurvivorsSickle Cell & Young Stroke Survivors...
-
Researchers ID key drivers of heart complications in sickle cell anemiaStudy opens path to earlier diagnosis, t...
-
Phase 1 trial to test under-the-skin injection of sevuparin in sickle cell patientsModus Therapeutics is going to launch ...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.