Or register here
Global Search

Trusted Resources: Evidence & Education

Scientific literature and patient education texts

Back to Evidence & Education / Patient Education

Fact Sheet: Sickle Cell Trait

key information

source: St. Jude Children’s Research Hospital

year: N/A

summary/abstract:

It is possible for a person of any race or nationality to have sickle cell trait, but it is very common in African-Americans. About one (1) out of every 12 African-Americans has sickle cell trait. It also affects Hispanics, and people whose ancestors came from Africa, Latin America, Asia, India, and the Mediterranean region.

Sickle cell trait affects the red blood cells.

All red blood cells contain hemoglobin, which carries oxygen from the lungs to all parts of the body.

People with sickle cell trait have both normal hemoglobin A and abnormal hemoglobin S in their red blood cells.

People who do not have sickle cell trait or any other abnormal hemoglobin have red blood cells that contain only hemoglobin A.

People with sickle cell trait do not develop sickle cell disease.

People with sickle cell disease have red blood cells that contain mostly hemoglobin S. Under certain conditions these red blood cells become
sickle-shaped (banana-shaped) and block circulation.

read more

Related Content

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close

© 2026 rareLife solutions Inc.

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close