Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Systematic and Meta-Analytic Review: Medication Adherence Among Pediatric Patients With Sickle Cell Disease
source: Journal of Pediatric Psychology
year: 2016
authors: Loiselle K, Lee JL, Szulczewski L, Drake S, Crosby LE, Pai AL
summary/abstract:OBJECTIVE:
To provide a comprehensive summary (systematic review) of medication adherence rates by assessment method and medication type for pediatric patients with sickle cell disease (SCD), as well as identify important correlates for future research.
METHODS:
Articles assessing medication adherence and published between 1982 and February 2015 (n = 49) were identified using electronic databases. A meta-analysis of 14 studies examining demographic, medical, and psychosocial factors and medication adherence was conducted.
RESULTS:
Adherence rates ranged from 12% to 100% across all medications. Approximately 30% of studies reported associations between adherence and key demographic, medical, and psychosocial correlates. Mean effect sizes were small to moderate (r = .02-.53).
CONCLUSIONS:
The wide range of adherence rates reported in the literature may be because of, in part, the use of variable assessment strategies. Future studies examining pediatric SCD adherence should incorporate key correlates with the goal of replication.
DOI: 10.1093/jpepsy/jsv084
read more full text
Related Content
-
The Role of Pain Rehabilitation in an Adolescent Sickle Cell Disease Population: A Case SeriesSickle cell disease is an inherited hemo...
-
Podcast: How New Gene Therapies for SCD May Impact Women’s FertilityAs we closed 2023, the Food and Drug Ad...
-
Don’t Overlook Eye CareAs I sit waiting for my sister in the su...
-
The Bad Blood: My Life With Sickle Cell AnaemiaI wake up with an active volcano for a c...
-
Paulette E. Forbes, MPH, MS, APNMs. Paulette E. Forbes serves as an inpa...
-
How a Man and Woman, Both with a Sickle Cell Anemia Mutation, Had a Healthy ChildA man and woman who are both carriers of...
-
Increasing Appointment Attendance: A Vital Opportunity to Improve Health Outcomes for Those Living with Sickle Cell ...Sickle cell disease (SCD) affects approx...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.