Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Emotion-Focused Avoidance Coping Mediates the Association Between Pain and Health-Related Quality of Life in Children With Sickle Cell Disease
source: Journal of Pediatric Hematology/Oncology
year: 2019
authors: Lim CS, Karlson C, Edmond SN, Welkom JS, Osunkwo I, Cohen LL
summary/abstract:Sickle cell disease (SCD) is associated with pain and decreased health-related quality of life (HRQOL). Coping strategies influence pain but have not been evaluated as mediating the relation between pain and HRQOL in pediatric SCD. The current study examined whether pain-related coping mediates the association between pain and HRQOL in children and adolescents with SCD. In total, 104 children and adolescents 8 to 18 years of age (Mage=12.93 y) with SCD attending outpatient clinics completed pain intensity, HRQOL, and pain-related coping measures. Multiple mediation analyses were used to examine whether pain-related coping mediated the pain and HRQOL relation and whether types of coping (ie, approach, emotion-focused avoidance, problem-focused avoidance) were independent mediators. Total indirect effects for models examining physical and psychosocial HRQOL were not significant.
After controlling for covariates, emotion-focused avoidance significantly mediated the association between pain and physical HRQOL (effect: -0.023; bootstrapped SE: 0.018; 95% confidence interval: -0.0751, -0.0003) but not the pain and psychosocial HRQOL relation. Approach and problem-focused avoidance were not significant mediators. Coping with pain in pediatric SCD is an important avenue for clinical intervention and additional research. Among children with SCD reporting high pain intensity, interventions should emphasize negative impacts of emotion-focused avoidance coping and integrate other empirically supported coping strategies to improve HRQOL.
organization: University of Mississippi Medical Center, USA; Yale University School of Medicine, USA; VA Connecticut Healthcare System, USA; National Science Foundation, USA; The Levine Cancer Institute & Carolinas HealthCare System, USA; Georgia State University, USADOI: 10.1097/MPH.0000000000001429
read more
+myBinderRelated Content
-
Immunoglobulin G Responses Against Falciparum Malaria Specific Antigens are Higher in Children with Homozygous Sickl...Background: High Immunoglobulin G (IgG)...
-
Racism and Health-Related Quality of Life in Pediatric Sickle Cell Disease: Roles of Depression and SupportIntroductions: Sickle cell disease (SCD...
-
Cure Sickle Cell Now Move-On Virtual EventWe have re-imagined our annual Stomp Out...
-
Gene Therapy & Clinical Trials Webinarhttps://www.youtube.com/watch?v=yYexIUgH...
-
Jeffrey Lebensburger, MDDr. Lebensburger is a graduate of the Un...
-
Carla JonesAnyone affected by sickle cell disease k...
-
National Sickle Cell Awareness MonthSeptember is National Sickle Cell Awaren...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.