Dr. Walters is the director of Bone Marrow Transplantation at UCSF Benioff Children’s Hospital Oakland. He has been the Director of Stem Cell Therapy and a Division leader since 1999. During this period, he expanded his responsibilities to develop a career in stem cell transplantation in sickle cell disease. The integration of these areas of expertise has enabled him to develop a national program focusing on novel therapies for blood disorders.

Since joining Children’s Hospital, he has devoted his research career to pursuing curative therapies for hemoglobin disorders with an overarching goal of expanding this treatment more broadly to affected individuals. With NIH and industry support, he has conducted a number of multicenter clinical trials for sickle cell disease and thalassemia.

Currently, he is focused on initiating early phase clinical trials to test novel genomic editing techniques in hematopoietic stem cells (HCT) from individuals affected by hemoglobin disorders, starting with a high-profile trial in sickle cell disease. Other projects in the pipeline include activation of fetal hemoglobin by genomic editing in stem cells.

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