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John F. Tisdale, MD
Senior Investigator and Director
National Heart, Lung, and Blood Institute
10 Center Drive
Bethesda, Maryland, United States
John F. Tisdale, MD graduated from the College of Charleston in South Carolina with a B.A. in chemistry in 1986. He then earned his M.D. from the Medical University of South Carolina in 1990. Dr. Tisdale is currently working on multiple strategies both in the laboratory and in the clinic to cure sickle cell disease by repairing or replacing the precursor bone marrow cells that give rise to sickled red blood cells. Dr. Tisdale has an active research program in trying to characterize tolerance and create conditions in which patients will more easily tolerate donor cells and tissues without the need for destroying the immune system or perpetual use of immunosuppressant drugs. Dr. Tisdale and his colleagues also have an ongoing research agenda to find a gene therapy strategy for SCD. This project is in an earlier phase of development, although accrual to a protocol testing this approach has begun.
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