Dr. Isaac Odame is a staff physician and Medical Director of the Global Sickle Cell Disease Network at the Centre for Global Child Health at The Hospital for Sick Children, Toronto. He is also one of the founders of the Global Sickle Cell Disease Network based at The Hospital for Sick Children (SickKids) in Toronto. Dr. Odame played a leading role in the implementation of a newborn screening program for early detection and treatment of sickle cell disease in new born babies.

Dr. Isaac is also a Professor of Hematology/Oncology at the Department of Paediatrics, University of Toronto and the Hematology Division Director in the Department of Medicine. His academic work and clinical care focuses on patients with sickle cell disease, and thalassemias and other hematological disorders.

Representative Publications:

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

The severity of anaemia depletes cerebrovascular dilatory reserve in children with sickle cell disease: a quantitative magnetic resonance imaging study

Effectiveness of preoperative screening for sickle cell disease in a population with a newborn screening program: a cohort study

Assessment of cerebral blood flow with magnetic resonance imaging in children with sickle cell disease: A quantitative comparison with transcranial Doppler ultrasonography

Association of wheeze with lung function decline in children with sickle cell disease

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