Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
436 articlesFree, no login required
Looking for earlier coverage? Browse the news archive.
Distinct prokaryotic gut microbiome and proviral-immune axes of pathophysiology in Sickle Cell Disease
Sickle cell disease (SCD) is a chronic, inherited condition rising across the globe. Prior studies revealed a direct link between the gut microbiome and disease micropathology via…
Hydroxyurea and Gut Microbiome Interactions in Sickle Cell Disease: Toward Adjunctive Microbiome-based Therapy
Abstract Sickle cell disease (SCD) is a monogenic disorder marked by hemoglobin S polymerization, resulting in chronic hemolysis, vaso-occlusion, systemic inflammation, and…
Cause of death for Bexar County Jail inmate revealed as Sickle Cell Anemia
SAN ANTONIO - The official cause of death for a Bexar County Jail inmate who died in May has finally been released. According to the Bexar County Medical Examiner's Office, the…
Bexar County jail inmate died naturally of sickle cell disease, medical examiner rules
A woman who suffered a medical emergency in her cell at the Bexar County jail earlier this year died of complications from sickle cell disease, the Bexar County Medical Examiner's…
Trial Tests a New Gene-Editing Strategy for Sickle Cell Disease
The multicenter trial is evaluating a CRISPR-Cas9 approach designed to directly modify the beta‑globin gene in sickle cell disease. FDA-approved gene therapies have shown that…
Ugandans Urged to Embrace Early Screening for Sickle Cell Disease
Health experts have urged Ugandans to undergo screening for sickle cell disease, warning that many people are living with the inherited condition undiagnosed, exposing them to…
Cardiac Remodeling Patterns in Pediatric and Adolescent Patients with Sickle Cell Disease and Their Association with the Genotype and Clinical Severity of the Disease: A Systematic Review
Abstract Background: Sickle cell disease (SCD) is the most common inherited blood disorder globally, affecting approximately 300,000 newborns annually. Cardiac remodeling…
Medical Liaison - Hemoglobinopathies - Sickle Cell Disease - West
The Clinical, Medical and Regulatory (CMR) department at Novo Nordisk is one of the most diverse and collaborative groups within the organization. From healthcare provider…
Alloimmunization among Multiply Transfused Pediatric Patients with Sickle Cell Disease Attending Jaramogi Oginga Odinga Teaching and Referral Hospital, Kenya
Abstract Background: Sickle cell disease (SCD) is a major inherited haemoglobin disorder and a leading cause of childhood morbidity and mortality in sub-Saharan Africa. Repeated…
Blood Rheology After Allogeneic Hematopoietic Stem Cell Transplantation or Gene Therapy in Sickle Cell Disease
Abstract Allogeneic hematopoietic cell transplantation (HCT) and autologous hematopoietic stem cell–based gene therapies are potentially curative for sickle cell disease (SCD)…
Platelet Indices as Accessible Biomarkers for Risk Stratification in Pediatric Sickle Cell Disease: A Kenyan Cohort Study
Main Points High MPV and neutrophils with low PNR may act as accessible hematological signatures for VOC and ischemic stroke in pediatric SCD. Platelet indices could serve as…
Cochlear Implantation in Sickle Cell Disease: A Systematic Review of Feasibility and Outcomes
Abstract Introduction: Sickle cell disease (SCD) is associated with systemic complications, including sensorineural hearing loss (SNHL) from microvascular occlusion and chronic…