Clinical Trials and Research1 min read
Alloimmunization among Multiply Transfused Pediatric Patients with Sickle Cell Disease Attending Jaramogi Oginga Odinga Teaching and Referral Hospital, Kenya
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Abstract
Background: Sickle cell disease (SCD) is a major inherited haemoglobin disorder and a leading cause of childhood morbidity and mortality in sub-Saharan Africa. Repeated blood transfusions, although life-saving, increase the risk of red blood cell (RBC) alloimmunization, complicating future transfusions and predisposing patients to haemolytic transfusion reactions.
BiologicalSciences
Aims: This study determined the prevalence and determinants of RBC alloimmunization among multiply transfused children with SCD attending Jaramogi Oginga Odinga Teaching and Referral Hospital, Kisumu, Kenya.