Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Colchicine Protects Against Sickle Cell Related Cardiomyopathy: Evidence of the Novel Role of Inflammaging
Abstract Sickle cell disease (SCD) is a globally distributed hereditary red cell disorder with still high mortality. Growing evidence indicates that sickle cell related…
VAS-101 May Offer Promise in Patients With SCD
VAS-101, a topical curcumin gel applied under the tongue, is safe and well tolerated in patients with sickle cell disease (SCD), according to results from a phase 1 pilot study…
Sickle Cell Disease Linked to Higher Postpartum LARC Use
TOPLINE People with sickle cell disease (SCD) had 82% higher odds of receiving immediate postpartum long-acting reversible contraception (LARC) than those without SCD in a study…
Sickle Cell Disease: From Ancient Origins to Modern Breakthroughs in Gene Therapy
In the manuscript “Sickle Cell Disease: From Ancient Origins to Modern Break-2 throughs in Gene Therapy” by Drs. Bawo Ikolo et al, the authors examine various aspects of sickle…
Nonmyeloablative and reduced-intensity conditioning for allogeneic hematopoietic stem cell transplantation in sickle cell disease: a narrative review of safety, engraftment, and graft-versus-host-disease outcomes in adults and high-risk populations
Abstract Allogeneic hematopoietic stem cell transplantation (HSCT) is the only widely available cure for sickle cell disease (SCD), yet its use in adults has historically been…
Incidence of clinical malaria and asymptomatic parasitaemia among African children living with sickle cell disease: a multicentre prospective longitudinal cohort study protocol
Abstract Introduction Sickle cell disease is a monogenic blood disorder prevalent in Africa, where malaria poses a health risk for affected individuals. Individuals with sickle…
Premature blood stem cell aging in sickle cell disease may be reversible
Scientists at St. Jude Children’s Research Hospital found that prematurely old blood stem cells from sickle cell disease may be treatable with anti-aging drugs, and highlight a…
Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease
A promising approach for the treatment of genetic diseases is called gene therapy. Gene therapy is a relatively new field of medicine that uses genetic material (mostly DNA) from…
Virginia invests nearly $15 million to expand Medicaid access to sickle cell gene therapies
Gene therapy is offering new hope for people with sickle cell disease. Here's how Virginia's latest Medicaid funding could expand access to treatment. NORFOLK, Va. — 42-year-old…
Jharkhand Waives 75% Attendance Rule For Students With Sickle Cell Disease, Thalassaemia, Chronic Illnesses
In a significant step towards making school education more inclusive, the Jharkhand Cabinet on Tuesday approved a Standard Operating Procedure (SoP) exempting students suffering…
Agios scraps sickle cell treatment after trial shows limited benefit
July 21 (Reuters) - Agios Pharmaceuticals (AGIO.O) , opens new tab said on Tuesday it is discontinuing development of its sickle cell disease treatment after trial results failed…
Doctors misjudge SCD clinical trial motivations, US study finds
Suggestions target more effective communication to boost patient participation In the U.S., doctors who care for people with sickle cell disease (SCD) often don’t have a clear…