Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Abstract Bordetella hinzii is a rare, opportunistic Gram-negative bacterium traditionally associated with poultry but increasingly identified as a human pathogen in…
Highlights Sickle cell trait can cause severe, transfusion-dependent hematuria -- not always benign; requires thorough evaluation. Consider renal papillary necrosis for recurrent…
Abstract Sickle cell disease (SCD) is a type of inherited disorder of hemoglobin characterized by recurring vaso-occlusive pain crises that affect many organ systems. Although it…
Abstract Pregnancy in Sickle Cell Disease (SCD), a severe hereditary genetic condition, highly prevalent in Sub-Saharan African countries, is associated with increased risk of…
Orbital compression syndrome (OCS), also referred to in the sickle cell disease (SCD) literature as orbital infarction syndrome, is an uncommon but potentially sight-threatening…
Abstract Sickle cell disease (SCD) is a monogenic hemoglobinopathy in which hemoglobin S (HbS) polymerizes on deoxygenation, leading to sickling of red blood cells (RBCs) and…
Abstract Background: Sickle cell disease (SCD) is a major cause of morbidity and mortality among children in sub-Saharan African. Hydroxyurea (HU) remains the cornerstone of…
Background: Sickle Cell Disease (SCD) causes acute and chronic complications. Hydroxyurea (HU) reduces vaso-occlusive crises (VOCs), and improves patients’ outcomes. However…
Zydus Lifesciences is advancing its clinical pipeline with permission to start Phase III clinical trials of Desidustat, an oral therapeutic candidate for Sickle Cell Disease. The…
Abstract Sickle cell disease (SCD) is a globally distributed hereditary red cell disorder with still high mortality. Growing evidence indicates that sickle cell related…
TOPLINE People with sickle cell disease (SCD) had 82% higher odds of receiving immediate postpartum long-acting reversible contraception (LARC) than those without SCD in a study…
In the manuscript “Sickle Cell Disease: From Ancient Origins to Modern Break-2 throughs in Gene Therapy” by Drs. Bawo Ikolo et al, the authors examine various aspects of sickle…
