Clinical Trials and Research1 min read
Platelet Indices as Accessible Biomarkers for Risk Stratification in Pediatric Sickle Cell Disease: A Kenyan Cohort Study
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Main Points
High MPV and neutrophils with low PNR may act as accessible hematological signatures for VOC and ischemic stroke in pediatric SCD.
Platelet indices could serve as low-cost risk stratification tools for timely referrals in rural facilities with limited advanced imaging
Abstract
Sickle cell disease is a significant health challenge in Kenya, often associated with complications that result in 50-90% mortality if undiagnosed. This necessitates accessible phenotype-based biomarkers for risk stratification in resource-limited settings that handle majority of the SCD cases in the Kenyan population.