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Researchers ID key drivers of heart complications in sickle cell anemia
Study opens path to earlier diagnosis, targeted therapies.
Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death. The study opens a path to earlier noninvasive diagnosis and development of new targeted therapies to help SCA patients live longer with better quality of life.
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This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.