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Johns Hopkins researchers offer new protocol to potentially cure sickle cell disease

There’s new hope for patients who have blood diseases. Johns Hopkins Kimmel Cancer Center researchers say a new protocol offers the possibility of a cure. One patient who tried the treatment says it didn’t just change her life, it saved it.

For most of her life, Simone Day had a very different experience at the hospital than the one she’s having now. For Day, sickle cell meant acute pain crises. She’d be in the hospital for weeks. “I was essentially OK with dying at that point,” Day said. It’s different now, thanks to a bone marrow transplant in 2017.

The new protocol doesn’t only mean using what they call “half matched” donors, like Day’s mother, but also lowering the dosages of chemotherapy to make it safer on the patient.



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