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Healthy red blood cells owe their shape to muscle-like structures
Red blood cells are on a wild ride. As they race through the body to deliver oxygen, they must maintain a distinct dimpled shape—and bounce back into form even after squishing through narrow capillaries. Red blood cells that can’t keep their shape are associated with diseases like sickle cell anemia.
In a new study, Velia Fowler, PhD, and her lab at The Scripps Research Institute report that a protein called myosin IIA contracts to give red blood cells their distinctive shape. The findings, published this week in the journal Proceedings of the National Academy of Sciences, could shed light on sickle cell diseases and other disorders where red blood cells are deformed.
videos & visualsIU Nurse Invents Medical Device for People With Sickle Cell Diseasehttps://www.youtube.com/watch?v=TjE3Urth...
education & researchIdentifying central sensitization in adults with sickle cell disease: Differences in clinical features and psychobeh...Central sensitization (CS) has been iden...
education & researchSickle-Cell Disease Co-Management, Health Care Utilization, and Hydroxyurea UseBackground: Sickle-cell disease (SCD) ca...
people & placesJohn T. Horan MD, MPHJohn T. Horan, MD, MPH, is Associate Pro...
people & placesThe Brookdale University Hospital and Medical CenterThe Comprehensive Pediatric Sickle Cell ...
people & placesKenneth R. Peterson, PhDKenneth R. Peterson is the Professor and...
videos & visualsProviding Expert Care for Pregnant Sickle Cell Patienthttps://www.youtube.com/watch?v=rTebitxq...
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This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.