Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Sickle Cell Disease (SCD)
source: Be The Match
year: N/A
summary/abstract:Sickle cell disease (SCD) is a disease of hemoglobin, a molecule that carries oxygen within red blood cells. In SCD, defective hemoglobin causes the red blood cells to become stiff instead of flexible and form a sickle or a crescent.
SCD is an inherited disease, meaning that the disease is passed on from parents to children through genes. Genes are instructions that tell the body how to make all the different substances the body needs to work properly. Since SCD is inherited, the disease is present at birth.
In SCD, a child inherits two defective hemoglobin genes (called hemoglobin S), one from each parent. This causes the body to make faulty hemoglobin. If a child inherits just one defective hemoglobin S gene, and the other hemoglobin gene is normal (hemoglobin A), he or she will have sickle cell trait, and will not have any SCD symptoms.
read more
Related Content
-
Hydroxyurea improves lung function in children with sickle cell diseaseFor the first time, researchers were abl...
-
bluebird bio Presents New Data from HGB-205 Study of LentiGlobinTM Drug Product in Patients with Transfusion-Depende...First patient with severe sickle cell di...
-
First Sickle Cell Patient Dosed in Phase 2a of IMR-687This morning, Imara Inc. announced that ...
-
Muscle Structural, Functional and Energetic Benefits of Endurance Exercise Training in Sickle Cell DiseaseSickle cell disease (SCD) patients displ...
-
Sickle Cell Trait and the Risk of ESRD in BlacksBlacks, compared with whites, have an in...
-
Johns Hopkins researchers offer new protocol to potentially cure sickle cell diseaseThere's new hope for patients who have b...
-
ASH launches sickle cell disease clinical trials network to accelerate therapy developmentASH launched a clinical trials network d...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.