Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Charmaine Royal Leads $5 Million Effort to Decode Sickle Cell Pain
Marie Claire Chelini, Trinity Communications What if one disease could unlock insights into dozens of diseases? This is the ambition underlying a new federal grant led by…
Sickle Cell Disease: Can genetic variability influence pregnancy outcomes?
Abstract Pregnancy in Sickle Cell Disease (SCD), a severe hereditary genetic condition, highly prevalent in Sub-Saharan African countries, is associated with increased risk of…
Internationally recognized expert leads University of Maryland School of Medicine program in sickle cell disease
Enrico M. Novelli, MD, MS , has been named Director of the University of Maryland School of Medicine (UMSOM) Program in Sickle Cell Disease and a Professor in the Department of…
Socioeconomic Disparities Associated With Higher SCD Mortality in Colombia
Between 2012 and 2023, sickle cell disease (SCD) mortality increased in Colombia and was significantly higher in socioeconomically disadvantaged regions, according to findings…
Orbital Compression Syndrome Mimicking Severe Malaria in a Child with Sickle Cell Disease in a Ugandan Refugee Settlement: A Case Report
Orbital compression syndrome (OCS), also referred to in the sickle cell disease (SCD) literature as orbital infarction syndrome, is an uncommon but potentially sight-threatening…
Oxygen Timing as Therapy: Molecular Rationale and Clinical Imperative for Early Oxygen Administration in the Sickle Cell Disease Vaso-Occlusive Crisis—A Structured Narrative Review with Implications for Resource-Constrained Health Systems
Abstract Sickle cell disease (SCD) is a monogenic hemoglobinopathy in which hemoglobin S (HbS) polymerizes on deoxygenation, leading to sickling of red blood cells (RBCs) and…
Impact of hydroxyurea use on severity and hematologic profile in children with sickle cell disease at University of Benin Teaching Hospital, Benin city, Nigeria
Abstract Background: Sickle cell disease (SCD) is a major cause of morbidity and mortality among children in sub-Saharan African. Hydroxyurea (HU) remains the cornerstone of…
Sickle Cell Anemia Testing And Screening Market Size To Exceed $1.58 Billion By 2035 | SNS Insider
The global Sickle Cell Anemia Testing and Screening Market is expected to experience significant growth over the next decade as healthcare systems worldwide strengthen early…
‘Beloved’ Mom of 4 Dies After Contracting Salmonella Infection from Contaminated Ice on Overseas Trip
NEED TO KNOW Ayla Garcia, a 36-year-old mother of four from Virginia, has died after contracting a Salmonella infection on a mission trip to Kenya Her illness was complicated by…
India close to developing drug for sickle cell disease as Zydus-ICMR candidate enters phase III trials
India's efforts to develop an effective treatment for the neglected disease sickle cell anaemia have received a significant boost, with Zydus Lifesciences' drug candidate…
Hydroxyurea treatment for sickle cell disease in Nairobi informal settlements: A retrospective cohort study
Background: Sickle Cell Disease (SCD) causes acute and chronic complications. Hydroxyurea (HU) reduces vaso-occlusive crises (VOCs), and improves patients’ outcomes. However…
Zydus Lifesciences Gets Green Light For Phase III Desidustat Trial In Sickle Cell Patients
Zydus Lifesciences is advancing its clinical pipeline with permission to start Phase III clinical trials of Desidustat, an oral therapeutic candidate for Sickle Cell Disease. The…