DISCLAIMERThe information and materials accessed through or made available for use on any of our Sites, including, any information about diseases, conditions, treatments, or medicines, are for informational purposes only. The Content is not intended to be and is not a substitute for professional medical advice, diagnosis, or treatment, and your participation on our Sites does not create a healthcare professional-patient relationship. You should consult a doctor or other qualified health care professional regarding any questions you have about your health or before making any decisions related to your health or wellness. Call your doctor or 911 immediately if you think you may have a medical emergency.
Trusted Resources: News & Events
Latest announcements and gatherings
University researchers have developed computational methods using a supercomputer that enables them to dive deep inside sickle cells and analyze their molecular characteristics. By modeling the processes responsible for sickle cell formation, the team will be able to explore possible treatments for the disease.
Sickle cell anemia is caused by a genetic mutation that makes normally concave, round red blood cells become stiff and misshapen, said George Karniadakis, professor of applied mathematics. Sickle cell was identified as the first molecular disease by Nobel laureate Linus Pauling in 1949.
Pauling’s initial characterization was based on the behavior of hemoglobin, a molecule normally distributed evenly throughout the red blood cell. In an infected individual, the molecule “will self-assemble into a fiber, and this fiber will push the red blood cell into a sickle shape,” said Lu Lu GS, the study’s first author and a member of Karniadakis’ research group.
education & researchSickle Cell DiseaseSickle cell disease (SCD) is a group of ...
education & researchPotential therapeutic action of nitrite in sickle cell diseaseSickle cell disease is caused by a mutan...
news & eventsComputer models provide new understanding of sickle cell diseaseComputer models developed by Brown Unive...
news & eventsCorinna Schultz, MD: Does Sickle Cell Trait Get Discussed?According to data presented tonight at t...
news & eventsHealthy red blood cells owe their shape to muscle-like structuresRed blood cells are on a wild ride. As t...
people & placesMarina Jerebtsova, PhDDr Marina Jerebtsova is an assistant pro...
news & eventsSmall chips, big impact: MSU researcher studies cardiovascular, sickle cell diseaseA Mississippi State University researche...
send a message
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.