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Sickle Cell Disease

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source: Sickle Cell 101


What is sickle cell disease?
Sickle cell disease is a genetic blood disorder, meaning it is inherited through families. The disease is characterized by sickle-shaped red blood cells. These red blood cells take on an unusual shape, which makes it difficult for sickle red blood cells to maneuver through blood vessels. There are several types of sickle cell diseases. The most common include: Sickle Cell Anemia, Sickle C Disease, and Sickle Beta Thalassemia.

Sickle Cell Disease Inheritance
Sickle cell disease is inherited from both parents; therefore each parent must carry the “sickle cell gene” in order to pass it on to their children. Individuals that carry the “sickle cell gene” have either sickle cell disease or have sickle cell trait. Depending on their genotypes, there are several ways (and probabilities) to pass on the “sickle cell gene”. Both parents must carry a sickle cell gene in order for a child to inherit sickle cell disease.

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