Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Hand Foot Syndrome in Sickle Cell Anemia
source: Family Practice Notebook
year: 2018
summary/abstract:Hand Foot Syndrome in Sickle Cell Anemia:
II. Epidemiology
Often the first vaso-Occlusion crisis finding in young children
Occurs in up to 50% of children with Sickle Cell Anemia by the age of 2 years
Rare over age 4 years old
III. Pathophysiology
A. Not to be confused with Hand Foot Syndrome that occurs with certain Chemotherapy agents in non-sickle disease
B. Occurs in Sickle Cell Anemia with vaso-Occlusion
C. Caused by infarction of Bone Marrow
1. Metacarpal or Metatarsal Bones and phalanges
IV. Symptoms
Painful swelling and tenderness of either the hand or foot
Digits may appear mildly erythematous
Related Content
-
Acute Care Utilization at End of Life in Sickle Cell Disease: Highlighting the Need for a Palliative ApproachBackground: People with sickle cell dis...
-
SCA Therapy Hydroxyurea Doesn’t Boost Malaria Risk in Sub-Saharan Africa, Study FindsHydroxyurea, a treatment recommended for...
-
Retinopathy and Sickle Cell DiseaseSickle cell disease is a disorder that c...
-
Fighting Through Our Pain TV with Thomas J. Harrington MDhttps://www.youtube.com/watch?time_conti...
-
SCDAA Teams with MedicAlert Foundation to Improve Emergency Outcomes During Sickle Cell Crises[Hanover, Md., June 26, 2023] – The Si...
-
Reproductive Issues for Women With Sickle Cell Diseasehttps://www.youtube.com/watch?v=4vo_BPBn...
-
More Online Queries in Winter Suggest Seasonal Variations in SCD ActivityMore people search for information on si...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.