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What Causes Sickle Cell Disease?

key information

source: National Heart, Lung and Blood Institute

year: 2020

summary/abstract:

Abnormal hemoglobin, called hemoglobin S, causes sickle cell disease (SCD).

The problem in hemoglobin S is caused by a small defect in the gene that directs the production of the beta globin part of hemoglobin. This small defect in the beta globin gene causes a problem in the beta globin part of hemoglobin, changing the way that hemoglobin works.

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