Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Volume of white matter hyperintensities is an independent predictor of intelligence quotient and processing speed in children with sickle cell disease
source: British Journal of Haematology
year: 2015
authors: van der Land V, Hijmans CT, de Ruiter M, Mutsaerts HJ, Cnossen MH, Engelen M, Majoie CB, Nederveen AJ, Grootenhuis MA, Fijnvandraat K
summary/abstract:Sickle cell disease can be complicated by cerebral white matter hyperintensities (WMHs), which are associated with diminished neurocognitive functioning. The influence of the total volume of WMHs on the degree of neurocognitive dysfunction has not yet been characterized. In our study of 38 patients (mean age 12·5 years) we demonstrated that a higher volume of WMHs was associated with lower full-scale intelligence quotient (IQ), verbal IQ, Processing Speed Index and more fatigue. Our results suggest that volume of WMHs is an additional parameter to take into account when planning individual diagnostic and treatment options.
organization: Emma Children's Hospital, Academic Medical Centre, AmsterdamDOI: 10.1111/bjh.13179
read more full text
Related Content
-
Blood in your urine? Don’t delay, See your healthcare provider today!Sometimes people with sickle cell trait ...
-
Pathophysiology and treatment of pulmonary hypertension in sickle cell diseasePulmonary hypertension affects ∼10% of...
-
Virtual Reality Helps Reduce Pain Among Patients With Sickle Cell DiseaseImmersive virtual reality appeared effec...
-
Pain Criseshttp://68.media.tumblr.com/c7875137ded96...
-
SUSTAIN Clinical Trial Results Show Crizanlizumab Reduced Sickle Cell–Related Pain CrisesResults from the Phase 2 SUSTAIN clinica...
-
Gut Microbiome Translates Stress Into Sickle Cell CrisesA new study shows how chronic psychologi...
-
Fighting Through Our Pain TV with Thomas J. Harrington MDhttps://www.youtube.com/watch?time_conti...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.