Google
Trusted Resources: Evidence & Education
Scientific literature and patient education texts
The intersection between asthma and acute chest syndrome in children with sickle-cell anaemia
source: The Lancet
year: 2016
authors: DeBaun MR, Strunk RC
summary/abstract:Acute chest syndrome is a frequent cause of acute lung disease in children with sickle-cell disease. Asthma is common in children with sickle-cell disease and is associated with increased incidence of vaso-occlusive pain events, acute chest syndrome episodes, and earlier death. Risk factors for asthma exacerbation and an acute chest syndrome episode are similar, and both can present with shortness of breath, chest pain, cough, and wheezing. Despite overlapping risk factors and symptoms, an acute exacerbation of asthma or an episode of acute chest syndrome are two distinct entities that need disease-specific management strategies. Although understanding has increased about asthma as a comorbidity in sickle-cell disease and its effects on morbidity, substantial gaps remain in knowledge about best management.
organization: Vanderbilt-Meharry Sickle Cell Center for Excellence, Vanderbilt University School of Medicine,Nashville; Washington University School of MedicineDOI: 10.1016/S0140-6736(16)00145-8
read more full text
+myBinderRelated Content
-
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancyBACKGROUND: Pregnant women with sickle ...
-
The spectrum of sickle hemoglobin-related nephropathy: from sickle cell disease to sickle traitRenal dysfunction is among the most comm...
-
Sickle Cell & PregnancySickle cell disease often becomes more s...
-
The Role of Sleep Impairments on Pain Severity in Adults With Sickle Cell DiseaseSleep is a complex process and impairmen...
-
Multidisciplinary Care Team Greatly Reduces Risk in Pregnant SCD Patients in Low-income CountriesAccording to a study published in the Am...
-
Marina Jerebtsova, PhDDr Marina Jerebtsova is an assistant pro...
-
New Research Suggests SANGUINATE™ Reduces the Number of Sickled Red Blood Cells in Patients with Vaso-Occlusive Cr...SANGUINATE™, the only investigational ...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.