Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Sickle Cell Disease
source: Pfizer Inc.
Sickle cell disease, a rare hematological disease, results in misshapen red blood cells that can block the flow of blood through the body (called vaso-occlusive crises), causing intense pain, as well as problems such as stroke, acute chest syndrome, joint damage, kidney issues, occasionally even heart problems.
Sickle cell disease is a group of inherited red blood cell disorders that causes the cells to be crescent (“sickle”) rather than disk shaped. It is traced to abnormalities in hemoglobin, the protein that carries oxygen throughout the body.
Patients with the disorder are now living longer than they did in the past, thanks to a better understanding of how the disease works and earlier diagnosis and treatment. Creating a plan for managing symptoms of the disease is critical in improving patient outcome and requires close collaboration with healthcare providers. This collaboration is especially important when patients make the transition from seeing a pediatrician to seeing a doctor who treats adults.read more
Diabetes Drug, Metformin, Suggested as ‘Breakthrough’ Treatment for Sickle Cell AnemiaMetformin, a common drug for Type 2 diab...
Sickle cell disease and sickle cell carrier statusSickle cell disease is an inherited diso...
Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in children with sickl...Although allogeneic haematopoietic stem ...
FDA Approves Hydroxyurea Tablets for Pediatric Patients With Sickle Cell AnemiaThe US Food and Drug Administration (FDA...
FDA Approves First Targeted Therapy to Treat Patients with Painful Complication of Sickle Cell DiseaseToday, the U.S. Food and Drug Administra...
Gene-Editing Treatment Shows Promise for Sickle Cell DiseaseScientists are seeing promising early re...
FDA Awards $2M to Phase 2 Trial of Vitamin D for Reducing Risk of SCD Respiratory ComplicationsThe U.S. Food and Drug Administration (F...
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