Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Hand Foot Syndrome in Sickle Cell Anemia
source: Family Practice Notebook
year: 2018
summary/abstract:Hand Foot Syndrome in Sickle Cell Anemia:
II. Epidemiology
Often the first vaso-Occlusion crisis finding in young children
Occurs in up to 50% of children with Sickle Cell Anemia by the age of 2 years
Rare over age 4 years old
III. Pathophysiology
A. Not to be confused with Hand Foot Syndrome that occurs with certain Chemotherapy agents in non-sickle disease
B. Occurs in Sickle Cell Anemia with vaso-Occlusion
C. Caused by infarction of Bone Marrow
1. Metacarpal or Metatarsal Bones and phalanges
IV. Symptoms
Painful swelling and tenderness of either the hand or foot
Digits may appear mildly erythematous
Related Content
-
Cognitive Function may be Affected in Adults With Sickle Cell Disease, Study SuggestsAdults with sickle cell disease score wo...
-
Oral Manifestations of Sickle Cell DiseaseSickle cell disease is one of the most c...
-
Sickle Cell Anemia Treatment & ManagementThe National Institutes of Health advise...
-
Safety and early hints of benefit seen in phase 1b trial of PF-04447943Sickle cell disease (SCD) patients were ...
-
Vaso-Occlusive Pain Linked to Menstruation in Some Patients, Study FindsAcute vaso-occlusive pain is associated ...
-
SCA Therapy Hydroxyurea Doesn’t Boost Malaria Risk in Sub-Saharan Africa, Study FindsHydroxyurea, a treatment recommended for...
-
Retinopathy and sickle cellhttps://www.youtube.com/watch?v=i1awYgHl...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.