Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Does sickle cell disease increase risk of adverse outcomes following total hip and knee arthroplasty? A nationwide database study
source: The Journal of Arthroplasty
year: 2015
authors: Perfetti DC, Boylan MR, Naziri Q, Khanuja HS, Urban WP
summary/abstract:Sickle cell disease (SCD) is associated with impaired vascular function and progressive vaso-occlusive injury to bones. We used the Nationwide Inpatient Sample to identify all THA and TKA admissions between 1998 and 2010. After controlling for patient age, gender, insurance, race, and comorbidities, the risk of complication among admissions with SCD was 152% higher (P<0.001) for THA and 137% higher (P=0.001) for TKA. Patients with SCD had a length of stay that was 42% longer (P<0.001) for THA and 20% longer for TKA (P<0.001), and hospital charges that were 19% higher (P<0.001) for THA and 16% higher (P=0.001) for TKA. Orthopedic surgeons should counsel potential THA and TKA candidates with SCD of these risks prior to admission.
organization: SUNY Downstate Medical Center, Brooklyn; The Johns Hopkins University, BaltimoreDOI: 10.1016/j.arth.2014.10.035
read more full text
Related Content
-
Voxelotor in Adolescents and Adults With Sickle Cell Disease: Results of the Phase 3 Hope TrialBackground: Sickle cell disease (SCD) i...
-
Association of Hemoglobin S and C Traits with Kidney Disease in African Americans in the Reasons for Geographic and ...Background: Sickle cell trait (SCT) and ...
-
Sickle-Cell Patients See Hope in CRISPRSickle-cell disease is one of the most c...
-
Successful Gene Therapy for Sickle Cell DiseasePrior to this report, the only curative ...
-
Living With Sickle Cell Disease Is a Constant Battle With Pain, According to one Woman Who Has It“You don’t look sick.” That’s ...
-
Blood Transfusions: What You Need to Know and Do (Part 3: IRON OVERLOAD)https://www.youtube.com/watch?v=aXURPZav...
-
When Cracking Down On Opioids Means Tougher Access For Sickle Cell PatientsMany people with sickle cell disease wil...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.