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Sickle Cell Disease news and research updates

Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.

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  1. News

    New off-the-shelf gene editing may treat sickle cell without transplant

    Single dose safely corrected primate stem cells to levels considered curative An experimental, single-dose gene-editing therapy from Tessera Therapeutics successfully corrected…

  2. Modeling Genetic Diversity in Sickle Cell Disease Reveals Heterogeneous Responses to HbF-Inducing Therapies

    Abstract Sickle cell disease (SCD) is caused by a point mutation in the β-globin gene that promotes hemoglobin polymerization, leading to chronic hemolytic anemia, vaso-occlusive…

  3. The Journey of Gene Therapy in Sickle Cell Disease: How Molecular Advances Meet Clinical Care

    Highlights What are the main findings? Gene therapy for sickle cell disease has progressed from lentiviral gene addition strategies to precise genome editing approaches targeting…

  4. Frequency of emergency medical service utilization in sickle cell disease patients in Brazil

    Abstract Introduction: Sickle cell disease (SCD) is a genetic condition with serious complications, frequently necessitating emergency medical attention. This study aimed to…

  5. Business

    Sickle Cell Anemia Testing and Screening Market Report Scope & Overview:

    Sickle Cell Anemia Testing and Screening Market was valued at USD 494.8 million in 2025 and is expected to reach USD 1,579 million by 2035, growing at a CAGR of 12.30% from…

  6. SCD cure rate hits 95% with new stem cell transplant procedure

    Fertility also improved, with 2 successful pregnancies after treatment: Study Nearly every person with sickle cell disease (SCD) who underwent a new regimen for stem cell…

  7. Business

    Agios Pharmaceuticals Touts Strong AQVESME Launch as Sickle Cell Filing Advances

    Agios Pharmaceuticals AGIO executives said the company is focused on advancing mitapivat across rare hematologic diseases, highlighting early launch traction in thalassemia and a…

  8. News

    New era of sickle cell treatments reveals persistent system-wide barriers

    Despite rapid therapeutic advances in sickle cell disease, from red blood cell exchange to gene therapies, delivery remains constrained by infrastructure, geography, and care…

  9. Sickle cell disease and assessment of energy metabolism and serum cortisol in Lubumbashi

    Abstract Introduction: Sickle cell disease is an inherited red blood cells disorder which leads to oxidative stress and resulting in the disturbance of energy metabolism…

  10. News

    Govt aims at eliminating sickle cell anemia by 2047: Minister

    State Minister for Women and Child Welfare and Tribal Welfare Gummidi Sandhyarani has said the government is committed to providing health security to every tribal family…

  11. News

    New KGH facility to strengthen sickle cell treatment in north Andhra

    Vishakhapatnam : In a first-of-its-kind initiative in the government hospital sector in Andhra Pradesh, the state government has established a 'Centre of Competence for…

  12. Clinical, humanistic, and economic burden of sickle cell disease in The Jazan Region, Saudi Arabia

    Abstract Background Sickle cell disease (SCD) constitutes a significant public health concern in the Kingdom of Saudi Arabia (KSA), affecting a substantial proportion of the…