Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Sickle Cell Disease: Historical Overview and Current Therapies
Abstract Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry…
Exa-cel in Children with Transfusion-Dependent β-Thalassemia or Sickle Cell Disease
Abstract Background Exagamglogene autotemcel (exa-cel) is a cell therapy in which autologous CD34+ hematopoietic cells are engineered through ex vivo clustered regularly…
Lung function among children and adolescents with sickle cell disease living in Lake Victoria basin in Kenya
Abstract Introduction: Sickle cell disease (SCD) is a group of inherited blood diseases in which the affected person inherits two abnormal haemoglobin genes from both parents and…
How St. Jude research is transforming lives for patients with sickle cell disease
Courtney is an Ivy League–educated investment banker on Wall Street. She loves to travel, enjoys Broadway musicals and lives in New York City with her two best friends from…
Stem cell transplant for SCD beats gene therapy on cost: Study
Stem cell transplant from a partially matched donor is more cost-effective than gene therapy to treat sickle cell disease (SCD), according to a study. In order for currently…
Hydroxyurea Reduced Mortality for Children With Sickle Cell Anemia
A 10-year study in sub-Saharan Africa revealed that a higher dose of the oral medication Hydroxyurea improved survival and growth outcomes in children with sickle cell anemia …
Liberia: Screening and Early Intervention for Sickle Cell Disease Ultimately Save Countries Money - Dr. Maureen Achebe
Dr. Maureen M. Achebe is Clinical Director of Hematology, Brigham and Women's Hospital, Boston, Massachusetts. She is an Associate Professor of Medicine and Global Health Equity…
Closing the sickle cell disease-related health equity gap
June 19, marks World Sickle Cell Day, with the 2026 theme focusing on closing the survival gap and a push towards a universal cure. 20 years have passed since the WHO recognised…
The many facets of cardiopulmonary complications in sickle cell disease
Abstract Sickle cell disease (SCD) is a systemic vasculopathy, which progressively remodels the heart and pulmonary circulation through chronic anemia, hemolysis, and endothelial…
Fulcrum scraps sickle cell drug after FDA raises safety concerns
Fulcrum Therapeutics said it is discontinuing development of pociredir, its experimental oral treatment for sickle cell disease (SCD), after the U.S. Food and Drug Administration…
Research Confirms Hydroxyurea's Impact on Sickle Cell Anemia
Fewer serious complications. Fewer hospitalizations and blood transfusions. Better growth and development. And a markedly lower risk of death from the complications of sickle cell…
Correctseq Reports 15 Month Crisis Free Outcome in First Sickle Cell Disease Patient Treated With CS 206
CorrectSequence Therapeutics Co., Ltd. ( Correctseq ), a clinical-stage biotechnology company pioneering transformer Base Editing (tBE) technology for severe diseases, announced…