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For the last two decades, they’ve had the option of artificially fertilizing embryos and selecting only those that lack the sickle cell trait. Now a new possibility is on the horizon: They may soon be able to edit the offending gene right out of their own sperm, eggs or embryos, erasing it from their bloodline forever.
The technology that will allow this is called Crispr-Cas9. It’s relatively cheap and it permits scientists to change DNA with an ease and precision that until now has been impossible. The promise is that it will transform medicine by vanquishing previously incurable diseases. The method is probably at least a few years away from being applied in clinical settings. Still, some are already worried that, when it comes to improving our own genome, we don’t yet know enough about how genes work to wield this power without unintended consequences.
education & researchHydroxyurea for Sickle Cell Disease TreatmentHydroxyurea is a medicine used to reduce...
education & researchHaematopoietic stem cell transplantation for sickle cell disease – current practice and new approachesSickle cell disease is an inherited diso...
videos & visualsNashville Doctor Performs First Successful Gene Editing Procedure on Sickle Cell Anemia Patienthttps://www.youtube.com/watch?v=s7TPRomV...
news & eventsMatthew Porteus awarded grant for sickle cell anemia workThe California Institute for Regenerativ...
news & eventsSickle-Cell Patients See Hope in CRISPRSickle-cell disease is one of the most c...
news & eventsGene Therapy for Blood DisordersIn the context of intense scrutiny over ...
news & eventsThe Life, Death, and Dream of a Research Diversity Crusader“We want to have a nation in which the...
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This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.