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Sickle Cell Disease Research Shows Progress in Preventing Related Complications and Death

Studies aim to limit pain crises, prevent strokes in kids, and save the lives of pregnant women with SCD.

Sickle cell disease (SCD) is an inherited chronic disorder characterized by rigid, sickle-shaped red blood cells that get stuck in veins and block blood flow, which can cause severe pain, stroke, organ failure, and complications leading to death. Each year, approximately 300,000 people around the world are born with SCD, and most of them lack access to comprehensive care or effective treatment options. In fact, the only established long-term therapy for SCD, a pill called hydroxyurea approved more than a decade ago to treat complications stemming from the disease, is widely underused in resource-poor countries.

There is an enormous need to improve the quality of life for people with SCD and decrease global mortality rates. Three studies presented today during the 58th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego report on encouraging advances for SCD treatment that carry global public health implications.


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