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Sickle Cell Disease: After Years of Neglect Some Promise for Sufferers
It’s Black History Month, when the nation commemorates the many achievements and contributions of African Americans.
It’s also a time to reflect on certain health issues with significant mortality and morbidity that disproportionately afflict African Americans.
Sickle cell disease (SCD) is one such health problem. SCD is a group of congenital red blood cell disorders, named sickle cell for the crescent shape of red blood cells. SCD alters the structure of hemoglobin, the molecule in red blood cells that delivers oxygen to organs and tissue throughout the body. The most common SCD disorder type is sickle cell anemia.
SCD affects millions of people worldwide. In the U.S., approximately 100,000 individuals are living with the congenital disease. The disease predominantly impacts people of sub-Saharan African descent.
SCD causes significant morbidity, including severe pain, anemia, organ damage, and infections. The disease also leads to premature mortality.
education & researchDouble-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial)Blood cell membranes in sickle cell dise...
news & eventsAlzheimer’s Treatment Memantine Shows Promise in Treating Sickle Cell DiseaseMemantine, a standard treatment for Alzh...
news & eventsGBT Receives FDA Breakthrough Therapy Designation for Voxelotor for Treatment of Sickle Cell Disease (SCD)Global Blood Therapeutics, Inc. (GBT) to...
news & eventsMaxCyte, Inc. to Present Positive Preclinical Data for Sickle Cell DiseaseMaxCyte, a US-based global company dedic...
news & eventsbluebird bio Presents New Data from HGB-205 Study of LentiGlobinTM Drug Product in Patients with Transfusion-Depende...First patient with severe sickle cell di...
education & researchInitial results from a cohort in a phase 2a study (GBT440-007) evaluating adolescents with sickle cell disease treat...Sickle cell disease (SCD) is a genetic d...
news & eventsSafety and early hints of benefit seen in phase 1b trial of PF-04447943Sickle cell disease (SCD) patients were ...
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This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.