• Join Today!

Become a member and connect with:

  • An Active Online Community
  • Articles and Advice on SCD
  • Help Understanding Clinical Trials

Randomized Trials Needed to Assess Benefits of Salmonella Vaccines in SCD Patients, Study Says


Randomized controlled trials are needed to examine the benefits of vaccinating people with sickle cell disease (SCD) against salmonella infections, which can be particularly fatal to children with the disease, a study says.

The review study, “Vaccines for preventing invasive salmonella infections in people with sickle cell disease,” was published in the Cochrane Database of Systematic Reviews.

Among people with SCD, mortality is highest in children, with a rate of between 2 percent and 30 percent in the first five years of life. Many of these deaths are caused by severe infections, to which children with SCD are more susceptible.

The sickle shape of SCD red blood cells makes them more prone to getting stuck inside small blood vessels, including in the spleen, which can block the blood flow through this organ and cause a condition referred to as splenic sequestration.

 

https://www.onescdvoice.com/wp-content/uploads/2019/07/Salmonella-Vaccines-SCD.jpg

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close