Sickle Cell Disease research and publications
Research papers and conference abstracts relevant to sickle cell disease, with the citation details each record holds. Each one links to the version of record at the publisher.
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Sickle cell drug at high dose eases anemia symptoms in severe SCD
A high dose of pociredir, Fulcrum Therapeutics ’ oral drug candidate for sickle cell disease (SCD), boosted fetal hemoglobin (HbF) levels and reduced red blood cell destruction —…
Steve Bryson, PhDSickle Cell Disease2026
- ReferencePublished on mdpi.com
Birth Prevalence of Sickle Cell Disease in India: A Systematic Review and Meta-Analysis
Newborn screening helps identify sickle cell disorder (SCD) early and to promptly initiate effective measures. It is estimated that India accounts for approximately 16% of global…
Emine A. Rahiman, Rajendra Prasad Anne, * and Rajasekharan P. WarrierMDPI2026
- ReferencePublished on sicklecellanemianews.com
Early results of trial testing tebapivat in SCD expected later this year
A small clinical trial testing Agios Pharmaceuticals ’ oral therapy candidate tebapivat against a placebo for easing symptoms in people with sickle cell disease (SCD) has…
Marisa Wexler, MSSickle Cell Disease2026
- ReferencePublished on tandfonline.com
Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda
Background Sickle cell disease (SCD) is a genetic blood disorder most prevalent in Eastern and Western Africa. With the high prevalence of SCD in northern Uganda, we set out to…
Silvia Awor, Jimmyy Opee, Denis Ocaya and 5 othersTaylor & Francis2026
- ReferencePublished on pmc.ncbi.nlm.nih.gov
Laboratory and genetic characteristic associated with gallbladder-related outcomes in sickle cell disease in Brazil: results from the REDS-III multicenter cohort study
Sickle cell disease (SCD) is a hereditary disorder characterized by HBB variants, leading to chronic hemolytic anemia and vaso-occlusion. Hepatobiliary complications, including…
André Rolim Belisário, ✉, Mina Cintho Ozahata and 12 othersNational Library of Medicine2026
- ReferencePublished on sciencedirect.com
A Review of Sickle Cell Disease: Then and Now
Sickle Cell Disease (SCD) is a group of disorders associated with mutations in the β-globin (HBB) gene and defined by the presence of haemoglobin S (HbS). SCD affects millions of…
Oluwaseyi A. Odelana, Oluwatoyin M. AladejanaScienceDirect2026
- ReferencePublished on sicklecellanemianews.com
FDA awards breakthrough device status to sickle cell diagnostic test
The Food and Drug Administration (FDA) has granted breakthrough device designation to the Gazelle Hb Variant test, a point-of-care blood test developed by Hemex Health to enable…
Michela Luciano, PhDSickle Cell Disease2026
- ReferencePublished on pmc.ncbi.nlm.nih.gov
Curative Approach to the Treatment of Beta-Thalassemia and Sickle Cell Disease with Hematopoietic Stem Cell Transplantation
β-thalassemia and sickle cell disease are two inherited hematological diseases due to defective hemoglobin synthesis or to the production of hemoglobin with altered properties…
Ugo Testa, Germana Castelli, Elvira PelosiNational Library of Medicine2026
- ReferencePublished on mdpi.com
Rethinking Sickle Cell Disease as a Systemic Vasculopathy
Sickle cell disease (SCD) is the most common inherited clinically relevant blood disorder. Although a deceptively simple monogenetic disorder, the associated complications have…
Mariana DuPont, Najibah A. Galadanci, Rushil V. Patel and 2 othersMDPI2026
- ReferencePublished on sicklecellanemianews.com
Blood screen may spot potential complications in sickle cell children
Testing blood levels of certain clotting proteins may help clinicians identify serious complications of sickle cell disease (SCD) in children, a study showed, a finding that could…
Marisa Wexler, MSSickle Cell Disease2026
- ReferencePublished on sciencedirect.com
Red cell antigen exposures in patients with sickle cell disease receiving transfusion from Black and Hispanic donors
Patients with sickle cell disease (SCD) have an elevated risk for alloimmunization due to frequent transfusions and antigenic disparities with donors. Extended antigen matching…
Julia Mewha, Sunitha Vege, David F. Friedman and 4 othersScienceDirect2026
- ReferencePublished on pmc.ncbi.nlm.nih.gov
Accelerated brain atrophy in sickle cell anemia despite chronic exchange transfusion therapy—A case report
Neurovascular complications are a common and major cause of morbidity and mortality in patients with sickle cell anemia (SCA). Prior studies have demonstrated cortical thinning as…
Tales Santini, Jinghang Li, Jr-Jiun Liou and 8 othersNational Library of Medicine2026