Research and publicationsReference2026

Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda

Published by Taylor & Francis

The full paper is on tandfonline.com. What follows is its abstract, so you can judge whether to read on.

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Abstract

Background

Sickle cell disease (SCD) is a genetic blood disorder most prevalent in Eastern and Western Africa. With the high prevalence of SCD in northern Uganda, we set out to document the haematological profile of patients with SCD in Acholi sub-region of northern Uganda.

Methods

This was a cross-sectional study at Gulu University Teaching Hospitals from February to May 2025. Patients with SCD gave blood, which was analysed at GRRH, and the results were shared with their healthcare providers. Logistic regression was done to determine the association between the haematological parameters and hydroxyurea use.

Results

Four hundred eighteen blood samples were analysed. The mean age of the participants was seven years of age, and the median was 5 years of age, ranging from 1 to 28 years of age. About 95% of participants had anaemia, 92.1% erythropenia, and 92.6% low haemtocrit levels. Meanwhile, 47.9% of participants had leucocytosis and 49.1% thrombocytosis. Hydroxyurea use was associated with a normal platelet count (OR=0.35, 95% CI 0.18–0.65, p-value=0.001).

The text above is the abstract as published by Taylor & Francis. The original is at tandfonline.com.

Cite this

Silvia Awor, Jimmyy Opee, Denis Ocaya, Benard Abola, Geoffrey Maxwell Malinga, Christine Oryema, et al. Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda. Taylor & Francis. 2026.

Authors: Silvia Awor, Jimmyy Opee, Denis Ocaya, Benard Abola, Geoffrey Maxwell Malinga, Christine Oryema, Beatrice Arwenyo, Acaye Ongwech
Source: Taylor & Francis
Year: 2026

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