The Sickle Cell Association of Hillsborough County was established in 1976. For over 35 years, it has provided materials to educate persons with sickle cell concerning medical, sociological, and psychological implications of sickle cell disease and trait. Counseling is provided to individuals and families diagnosed through the Newborn Screening Program. Educational programs are conducted to community groups, health care providers, and public and private schools. The organization also provides medical and social services referrals to individuals and families affected by disease.

Their outreach programs seek to do the following:
-Openness and empathy for sickle cell disease/trait patients and their families
-Understanding the use of evidence-based strategies to prevent hospitalization and burdens on the system
-Teaching best treatment practices to healthcare providers and educating patients and their families about ways to live with this chronic condition with no cure
-Referrals to medical professionals for appropriate medical care, focused on improving outcomes
-Empowering our community through increased knowledge and awareness to contribute toward helping SCA find a cure
-Assisting patients with identifying resources and services to improve the quality of their lives
-Counseling patients with disease/trait and their families
-Health fairs which screen individuals and raise awareness about the condition