Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Frequency of emergency medical service utilization in sickle cell disease patients in Brazil
Abstract Introduction: Sickle cell disease (SCD) is a genetic condition with serious complications, frequently necessitating emergency medical attention. This study aimed to…
SCD cure rate hits 95% with new stem cell transplant procedure
Fertility also improved, with 2 successful pregnancies after treatment: Study Nearly every person with sickle cell disease (SCD) who underwent a new regimen for stem cell…
Sickle cell disease and assessment of energy metabolism and serum cortisol in Lubumbashi
Abstract Introduction: Sickle cell disease is an inherited red blood cells disorder which leads to oxidative stress and resulting in the disturbance of energy metabolism…
Clinical, humanistic, and economic burden of sickle cell disease in The Jazan Region, Saudi Arabia
Abstract Background Sickle cell disease (SCD) constitutes a significant public health concern in the Kingdom of Saudi Arabia (KSA), affecting a substantial proportion of the…
Treatment of Sickle Cell Anemia: Pharmacological, Transfusion, and Genetic Strategies
Sickle cell disease (SCD) is a prevalent hereditary hemoglobinopathy characterized by hemoglobin S (HbS) polymerization, resulting in chronic hemolysis, vaso-occlusion, and…
Plasma proteome signatures are predictive of mortality in sickle cell disease
Sickle cell disease (SCD) is associated with severe systemic complications and increased mortality risk. Predicting SCD severity is currently difficult because of a lack of…
CS-206 in Patients With Sickle Cell Disease
Overview The goal of this open label, single-arm clinical study is to learn about the safety and efficacy of CS-101 injection in treating sickle cell disease. Description CS-101…
Exploring the impact of haptoglobin gene polymorphisms and severity of sickle cell disease: meta-analysis and gene set enrichment study
Abstract Background: Sickle cell disease, a genetic blood disorder marked by vaso-occlusive crises and severe pain, presents a major global health challenge. Haptoglobin, a…
Tessera Therapeutics Showcases New Preclinical Data Advancing In Vivo Program in Sickle Cell Disease and CAR-T Applications at the American Society of Gene and Cell Therapy 29th Annual Meeting
Presented improved editing data in non-human primates (NHP) for sickle cell disease (SCD), demonstrating a single dose of Gene Writer achieved an average of 85% of long-term…
Compound Heterozygous Sickle Cell-Beta Thalassemia Presenting As Chronic Hemolytic Anemia With Microcytosis and Prominent Left Ventricular Trabeculation: A Case Report
Abstract Sickle cell-beta thalassemia, a compound heterozygous hemoglobinopathy, can be difficult to diagnose because clinical features and laboratory findings often overlap with…
Integration of Sickle Cell Screening with Routine Immunization in Mbujimayi, a Remote City in the Democratic Republic of the Congo
Abstract Background: Sickle cell disease is the most common genetic disorder in the world. It is a real public health problem in sub-Saharan Africa. Early screening makes it…
Acute Chest Syndrome in Children with Sickle Cell Disease: A Narrative Review
Abstract Acute chest syndrome (ACS) is a common pulmonary complication in children with sickle cell disease, defined by a new pulmonary infiltrate on imaging accompanied by fever…