Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Exploring plasma microRNA profiling and signaling pathways in comorbidity-free sickle cell anemia: a pilot case-control study
Sickle cell anemia (SCA) is associated with substantial end‑organ morbidity, yet the circulating microRNA (miRNA) landscape in clinically stable, comorbidity‑free adults with SCA…
Sickle cell doctors face higher burnout than other specialists: Study
Hematologists-oncologists who specialize in sickle cell disease (SCD) report higher levels of burnout than those not specializing in SCD, even though no differences in grit and…
Back to basics in sickle cell disease
Sickle cell disease—the subject of a new Seminar in The Lancet —is one of the most prevalent and fastest-growing genetic disorders worldwide. Although its true prevalence is…
Genetics and Genomics in Sickle Cell Disease in Africa
Advanced genomic technologies are revolutionizing our ability to understand complex diseases. Large‐scale population studies are needed to realize the potential of using…
- Clinical Trials and Researchclinicaltrials.ucsf.edu
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BMS-986470 in healthy…
How the Brain Compensates for Sickle Cell Disease
Summary: Sickle cell disease (SCD) is widely recognized as a blood disorder, but new research reveals its profound impact on the brain’s architecture. Using advanced MRI imaging…
Impact of Individualized versus Weight-Based Pain Protocols on Patient Satisfaction for Patients with Sickle Cell Disease Experiencing a Vaso-Occlusive Episode
National guidelines for the acute management of sickle cell disease (SCD) vaso-occlusive episodes (VOE) recommend use of a patient-specific (PSP) or a weight-based protocol. We…
- Clinical Trials and Researchhealth.osu.edu
Research lab seeks to meet unexpected challenges of sickle cell disease and reproductive health
Sickle cell disease (SCD) , an inherited blood disorder passed down through genes, shows up significantly more often in Black populations. In people with SCD, normal, rounded red…
Acupuncture with Bleeding Techniques and Autogenic Breathing for Sickle Cell Pain Crisis: A Case Report
Rhys May North Seattle Community Acupuncture and Wedgwood Acupuncture & Botanical Medicine Keywords: Case report, sickle cell anemia, pain, acupuncture, traditional Chinese…
Stroke burden and functional impacts in adults with sickle cell disease
Stroke in sickle cell disease (SCD) has been well characterized in children, but data in adults remain insufficient, particularly regarding long-term functional consequences. The…
Sickle Cell Oregon Globe
Staying Safe and Healthy This Winter As we move through February, cold weather remains a significant concern for our sickle cell community. Cold temperatures cause blood vessels…
Research and progress in sickle cell disease and thalassemia: a podcast with Baba Inusa
We’re joined by Baba Inusa (right), a pediatric hematologist and Professor at King’s College London (UK), to discuss research, progress, and the regenerative aspects of sickle…