Sickle Cell Disease news and research updates
Research readouts, treatment and access decisions, and community updates for people living with sickle cell disease and the people who care for them — each one dated, with a link to the original source where there is one.
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Effect of health educational intervention on early detection of sickle cell disease among adolescent population in tribal areas of East Singhbhum district, Jharkhand: A study protocol
Abstract Sickle Cell Disease (SCD) remains a public health challenge in India, particularly among tribal populations. Gaps persist in early detection, awareness, and culturally…
Gene Editing Therapy Succeeds in 96% of Sickle Cell Disease Patients
Editas Medicine has reported positive outcomes for a gene editing treatment to treat severe sickle cell disease, a hereditary blood disorder with limited treatment options…
The Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-cell Disease
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate…
Base Editing of HBG1 and HBG2 Promoters for Sickle Cell Disease
Sickle cell disease is characterized by chronic hemolytic anemia and recurrent severe vaso-occlusive crises. Ristoglogene autogetemcel (risto-cel) includes autologous CD34+…
Gene editing therapy shows success against severe sickle cell disease
New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options. After…
Powerful supercomputer simulations help Michael Graham understand blood flow in sickle cell disease
Blood is often pictured as a smooth, continuous stream, but in reality it behaves more like rush-hour traffic in a dense city with crowded lanes, sudden merges and countless tiny…
Increased prevalence of clonal hematopoiesis in children with sickle cell disease
Recent studies have reached opposing conclusions about whether clonal hematopoiesis (CH) is increased or decreased in patients with sickle cell disease (SCD). Given that CH is…
- Clinical Trials and Researchsicklecellanemianews.com
Chicago nurses lead charge to speed up SCD emergency care: Study
Through a project aimed at building empathy and understanding among clinicians about sickle cell disease (SCD)-related pain episodes, a team of nurses in Chicago has helped…
Evaluation of ADAMTS13 Activity and von Willebrand Factor Antigen Levels in Patients with Sickle Cell Anaemia
Omolola Kafayat Awolope Department of Medical Laboratory Science, Afe Babalola University, Ado Ekiti, Ekiti State, Nigeria. David Olufemi Adebo Department of Clinical Diagnostics…
Prenatal diagnosis of sickle cell disease by amniocentesis using FTA technology in a context of precariousness in sub-Saharan Africa: Challenges and perspectives
ABSTRACT Sickle cell disease (SCD) is the most common inherited hemoglobinopathy worldwide. Improving the quality of life of people with SCD requires prenatal and neonatal…
- Clinical Trials and Researchclinicaltrials.ucbraid.org
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Etavopivat is a new medicine under development for treating blood disorders like sickle cell disease and thalassaemia. Sickle cell disease and thalassaemia are inherited blood…
Adults with SCD face high risk of stroke in their 30s and 40s, study finds
Adults with sickle cell disease (SCD) face a substantial risk of stroke, most often in their 30s and 40s, with lasting physical disability and cognitive impairment, a new study…