Or register here
Global Search

Trusted Resources: People & Places

Healthcare providers, researchers, and advocates

Back to People / Researchers
Patrick C. Hines, MD, PhD

Patrick C. Hines, MD, PhD

Researcher
Assistant Professor in the Department of Physiology
Wayne State University School of Medicine
3901 Beaubien Street
Pediatrics Critical Care, Medicine
Detroit, Michigan, United States

Patrick C. Hines, MD, PhD is an experienced pediatric critical care physician (general and cardiac) and a vascular biology research scientist. He is also the Founder and CEO of Functional Fluidics, a startup company developing clinical bioassays to measure blood function during simulated flow with microliters of whole blood. This technology is being adopted by pharmaceutical companies, clinicians, and research scientists to evaluate new therapies for red blood cell disorders such as sickle cell disease, coagulation disorders, and cancer. Dr. Hines was selected to the inaugural class of the Aspen Global Leadership Network’s Health Innovators Fellowship. He was the Chairman of the board of directors for the SNMA in the past. Areas of Interest: Role of beta-adrenergic stimulation in erythrocyte adhesion to the pulmonary vasculature; mechanisms of sickle erythrocyte adhesion

Representative Publications:

Central nervous system events in children with sickle cell disease presenting acutely with headache

TR2/TR4 overexpression in a humanized sickle cell disease mouse model decreases RBC adhesion to VCAM-1

Epinephrine acts through erythroid signaling pathways to activate sickle cell adhesion to endothelium via LW-alphavbeta3 interactions

Novel epinephrine and cyclic AMP-mediated activation of BCAM/Lu-dependent sickle (SS) RBC adhesion

view profile

Related Content

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close

© 2025 rareLife solutions Inc.

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close