• Join Today!

Become a member and connect with:

  • An Active Online Community
  • Articles and Advice on SCD
  • Help Understanding Clinical Trials
scientific articles

Sickle cell disease in childhood: from newborn screening through transition to adult medical care

key information

source: Pediatric Clinics of North America

year: 2013

authors: Quinn CT


Sickle cell disease (SCD) is the name for a group of related blood disorders caused by an abnormal hemoglobin molecule that polymerizes on deoxygenation. SCD affects the entire body, and the multisystem pathophysiology begins in infancy. Thanks to prognostic and therapeutic advancements, some forms of SCD-related morbidity are decreasing, such as overt stroke. Almost all children born with SCD in developed nations now live to adulthood, and lifelong multidisciplinary care is necessary. This article provides a broad overview of SCD in childhood, from newborn screening through transition to adult medical care.

organization: Cincinnati Children's Hospital Medical Center; University of Cincinnati College of Medicine

DOI: 10.1016/j.pcl.2013.09.006

read more full text source